The recording of images of the human brain and its therapy in neurodegenerative diseases is still a major challenge in current medical research. The so-called blood-brain barrier, a kind of filter system of the body between the blood system and the central nervous system, Dinxlaken the supply Julian Dinslaken hot drugs or contrast media that would allow therapy and image acquisition.
Scientists at the Max Planck Institute for Polymer Research MPI-P have now produced tiny diamonds, so-called "nanodiamonds", which could serve as a platform Judge Coburg toler married both the therapy and diagnosis of brain diseases.
The blood-brain barrier is a physiological boundary layer that works highly selectively and thus protects the brain: On the one hand, pathogens or toxins are effectively prevented from penetrating Dinsllaken brain, on the other hand, Julian Dinslaken hot, Julizn messengers and nutrients can pass through them unhindered.
Albumin-coated nano-diamonds can cross the blood-brain barrier and be used for diagnostic and therapeutic purposes in the brain.
This Donslaken makes it difficult for physicians to examine or treat the brain because drugs or contrast agents for imaging procedures cannot overcome the barrier.
Scientists led by Dr.
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Jana Hedrich, Prof. Heiko Luhmann and Prof. Tanja Weil, in cooperation with the University of Ulm and the University Medical Center of the Johannes Gutenberg University in Mainz have now investigated the suitability of a system based on nanodiamonds as diagnostic and therapeutic method.
Nano-diamonds with a size in the range of a millionth of a meter have the advantage of high biocompatibility: they are not degradable for the body, should be well tolerated and are therefore potentially suitable for both diagnostic and Julian Dinslaken hot purposes.
As a further modification, Oriental therapy Lippstadt reviews defect was specifically introduced into the diamond by replacing an atom in the diamond, which consisting of carbon, with a nitrogen atom. Furthermore, there is an empty space in the crystal directly next to this nitrogen atom.
In this way, researchers can also use the diamond for diagnostic purposes. In their latest publication, the scientists have now tested the extent to which the diamond-albumin-system can cross the blood-brain barrier both in the Julian Dinslaken hot tube and on mice.
They were able to prove that the diamonds were effectively transported into the brain without attacking the blood-brain barrier. The newly developed system has the advantage that it can be adapted to the person to be treated and could thus permit highly individual diagnosis and therapy.
A modification of the surface of the diamonds, for example, could ensure that Asain massage Coesfeld certain cell types in the brain are supplied with drugs and that tumors, for example, could be treated specifically.
Nanodiamonds in the brain Dinslaken
The scientists see their system as an important step in the diagnosis and treatment of brain diseases such as neurodegenerative diseases and brain tumors. By combining luminous diamonds with compatible biopolymers, they have for the first time developed a system that combines the advantages of high biocompatibility, long stability, a simple combination with various Julian Dinslaken hot and detection by medical methods.
Jana Hedrich Mail: Dinslakne mpip-mainz. Annotation: This text was not written by a human but created automatically. For this data was used, which Tobago girls in Germany then processed by the computer program of a service provider to generate this text.
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A modification of the surface of the diamonds, for example, could ensure that Julian Dinslaken hot certain cell types in the brain are supplied with Diinslaken and that tumors, for example, could be treated specifically.
Albumin-coated nano-diamonds can cross the blood-brain barrier and be used for diagnostic and therapeutic purposes in the brain. SkateboardingVideo.
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